Inhibition of platelet aggregation by clopidogrel is fully on account of an Energetic metabolite. Clopidogrel is metabolized to this Lively metabolite in part by CYP2C19. .iloperidone increases levels of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Iloperidone is actually a time-dependent CYP3A inhibitor
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